Journal: Surgery in Practice and Science
Article Title: Prognostic value of tumor-infiltrating lymphocytes, tumor associated neutrophils and metabolic checkpoint molecules on survival of patients with metastatic pancreatic ductal adenocarcinoma
doi: 10.1016/j.sipas.2025.100320
Figure Lengend Snippet: Correlation heatmap with statistical significance represented by the pentagram. Heat map indicates clustering and positive correlation of TILs and MCMs with serum parameters of PDAC patients including CEA, CA19–9, Amylase, Lipase, Hb, Leukocytes, CRP, Creatinine, Bilirubin, GGT. Colors indicate Pearson r from 1 (red) to −1 (blue); ⭑⭑indicates a highly significant correlation ( p < 0.01), ⭑indicates a significant correlation ( p < 0.05). (Abbreviations: CEA: Carcinoma Embryonic Antigen; CA19–9: Carbohydrate antigen 19–9; Hb: Hemoglobin; CRP: C-reactive protein; Crea: Creatinine; ALP: alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; INR: international normalized ratio. Note: P stands for Primary tumor, M stands for metastasis tumor).
Article Snippet: We obtained secondary antibodies (horse anti-mouse IgG (BA-2000) and horse anti-rabbit IgG (BA-1100)) from VECTOR Laboratories (Burlingame, CA, USA), along with the Avidin/Biotin Blocking Kit (SP-2001) and UltraView Universal DAB Detection Kit, the alkaline phosphatase enzyme detection system (ABC-AP) (AK-5000), and the ImmPACT Vector Red Alkaline Phosphatase Substrate Kit (SK-5105).
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